Posts Tagged ‘Adam’

A modern take on the pericyclic electrocyclic ring opening of cyclobutene.

Saturday, November 26th, 2011
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Woodward and Hoffmann published their milestone article  “Stereochemistry of Electrocyclic Reactions” in 1965. This brought maturity to the electronic theory of organic chemistry, arguably started by the proto-theory of Armstrong some 75 years earlier. Here, I take a modern look at the archetypal carrier of this insight, the ring opening of dimethylcyclobutene.