I previously used data mining of crystal structures to explore the directing influence of substituents on aromatic and heteroaromatic rings. Here I explore, quite literally, a different angle to the hydrogen bonding interactions between a benzene ring and OH or NH groups.
Posts Tagged ‘Pyridine’
How does an OH or NH group approach an aromatic ring to hydrogen bond with its π-face?
Wednesday, June 22nd, 2016Exploring the electrophilic directing influence of heteroaromatic rings using crystal structure data mining.
Tuesday, June 21st, 2016This is a follow-up to the post on exploring the directing influence of (electron donating) substituents on benzene[cite]10.1021/acs.jchemed.5b00346[/cite] with the focus on heteroaromatic rings such indoles, pyrroles and group 16 analogues (furans, thiophenes etc).