Posts Tagged ‘MPEG’

Connections in chemistry. Anti-malaria drug ↔ organocatalysis.

Thursday, July 5th, 2012

Back in 1994, we published the crystal structure of the molecule below (X=H), a putative anti-malarial drug called halofantrine. Little did we realise that a whole area of organo catalysis based on a thiourea catalyst with a similar motif would emerge a little later. Here is how the two are connected.