Posts Tagged ‘MEP’

Aromatic electrophilic substitution: a different way of predicting regiospecificity

Saturday, April 4th, 2009

Every introductory course or text on aromatic electrophilic substitution contains an explanation along the lines of the resonance diagram shown below. With an o/p directing group such as NH2, it is argued that negative charge accumulates in those positions as a result of the resonance structures shown.