The anomeric effect is best known in sugars, occuring in sub-structures such as RO-C-OR. Its origins relate to how the lone pairs on each oxygen atom align with the adjacent C-O bonds. When the alignment is 180°, one oxygen lone pair can donate into the C-O σ* empty orbital and a stabilisation occurs. Here I explore whether crystal structures reflect this effect.
Posts Tagged ‘Carbon–oxygen bond’
A visualization of the anomeric effect from crystal structures.
Thursday, August 27th, 2015Tags:Alkane stereochemistry, Anomeric effect, Carbohydrate chemistry, Carbohydrates, Carbon–oxygen bond, Chemical bond, Chemical IT, Ether, Lone pair, Physical organic chemistry, Quantum chemistry, Stereochemistry, Technology/Internet
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