Posts Tagged ‘calculated free energy’

Mechanism of the solvatochromic reaction of a spiropyran.

Wednesday, February 4th, 2015

The journal of chemical education has many little gems providing inspiration for laboratory experiments. Jonathan Piard reports one based on the reaction below[1]; here I investigate the mechanism of this transformation.



  1. J. Piard, "Influence of the Solvent on the Thermal Back Reaction of One Spiropyran", Journal of Chemical Education, vol. 91, pp. 2105-2111, 2014.

The formation of cyanohydrins: re-writing the text books. ! or ?

Friday, March 4th, 2011

Nucleophilic addition of cyanide to a ketone or aldehyde is a standard reaction for introductory organic chemistry. But is all as it seems? The reaction is often represented as below, and this seems simple enough.