Detecting anomeric effects in tetrahedral boron bearing four oxygen substituents.

2 days ago
Henry Rzepa

In an earlier post, I discussed a phenomenon known as the "anomeric effect" exhibited by tetrahedral carbon compounds with four…

Internet Archeology: reviving a 2001 article published in the Internet Journal of Chemistry.

1 month ago

In the mid to late 1990s as the Web developed, it was becoming more obvious that one area it would…

Detecting anomeric effects in tetrahedral carbon bearing four oxygen substituents.

2 months ago

I have written a few times about the so-called "anomeric effect", which relates to stereoelectronic interactions in molecules such as…

Data Citation – a snapshot of the chemical landscape.

2 months ago

The recent release of the DataCite Data Citation corpus, which has the stated aim of providing "a trusted central aggregate…

Mechanistic templates computed for the Grubbs alkene-metathesis reaction.

2 months ago

Following on from my template exploration of the Wilkinson hydrogenation catalyst, I now repeat this for the Grubbs variant of…

3D Molecular model visualisation: 3 Million atoms +

3 months ago

In the late 1980s, as I recollected here the equipment needed for real time molecular visualisation as it became known…

The Macintosh computer at 40.

3 months ago

On 24th January 1984, the Macintosh computer was released, as all the media are informing us. Apparently, some are still…

A mechanistic exploration of the Wilkinson hydrogenation catalyst. Part 1: Model templates

3 months ago

Geoffrey Wilkinson first reported his famous work on the hydrogenation catalyst that now bears his name in 1965 and I…

Scholarly journals vs Scholarly Blogs.

4 months ago

First, a very brief history of scholarly publishing, starting in 1665 when scientific journals started to be published by learned…

Macrocyclic peptide antibiotics – now Zosurabalpin – then antibacterial agents based on cyclic D,L-α-peptide architectures.

4 months ago

Zosurabalbin,, is receiving a great deal of attention as a new class of antibiotic which can target infections for which current…