It is always rewarding when one comes across a problem in chemistry that can be solved using a continuous stream of rules and logical inferences from them. The example below is one I have been using as a tutor in organic chemistry for a few years now, and I share it here. It takes around 50 minutes to unravel with students.
- K. Harano, M. Eto, K. Ono, K. Misaka, and T. Hisano, "Sequential pericyclic reactions of unsaturated xanthates. One-pot synthesis of hydrobenzo[c]thiophenes", Journal of the Chemical Society, Perkin Transactions 1, pp. 299, 1993. http://dx.doi.org/10.1039/p19930000299