Posts Tagged ‘MEP’

Aromatic electrophilic substitution: a different way of predicting regiospecificity

Saturday, April 4th, 2009
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Every introductory course or text on aromatic electrophilic substitution contains an explanation along the lines of the resonance diagram shown below. With an o/p directing group such as NH2, it is argued that negative charge accumulates in those positions as a result of the resonance structures shown.