Posts Tagged ‘calculated free energy’

Mechanism of the solvatochromic reaction of a spiropyran.

Wednesday, February 4th, 2015
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The journal of chemical education has many little gems providing inspiration for laboratory experiments. Jonathan Piard reports one based on the reaction below[1]; here I investigate the mechanism of this transformation.

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References

  1. J. Piard, "Influence of the Solvent on the Thermal Back Reaction of One Spiropyran", Journal of Chemical Education, vol. 91, pp. 2105-2111, 2014. http://dx.doi.org/10.1021/ed4005003

The formation of cyanohydrins: re-writing the text books. ! or ?

Friday, March 4th, 2011
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Nucleophilic addition of cyanide to a ketone or aldehyde is a standard reaction for introductory organic chemistry. But is all as it seems? The reaction is often represented as below, and this seems simple enough.

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