Posts Tagged ‘anomeric effects’

Spotting the unexpected. The trifluoromeric effect in the hydration of the carbonyl group.

Friday, March 9th, 2012
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The equilibrium for the hydration of a ketone to form a gem-diol hydrate is known to be highly sensitive to substituents. Consider the two equilibria:

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Combichem: an introductory example of the complexity of chemistry

Sunday, December 19th, 2010
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Chemistry gets complex very rapidly. Consider the formula CH3NO as the topic for a tutorial in introductory chemistry. I challenge my group (of about 8 students) to draw as many different molecules as they can using exactly those atoms. I imply that perhaps each of them might find a different structure; this normally brings disbelieving expressions to their faces.

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